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Free-energy landscape of molecular interactions between endothelin 1 and human endothelin type B receptor: fly-casting mechanism

The free-energy landscape of interaction between a medium-sized peptide, endothelin 1 (ET1), and its receptor, human endothelin type B receptor (hETB), was computed using multidimensional virtual-system coupled molecular dynamics, which controls the system’s motions by introducing multiple reaction...

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Detalhes bibliográficos
Publicado no:Protein Eng Des Sel
Main Authors: Higo, Junichi, Kasahara, Kota, Wada, Mitsuhito, Dasgupta, Bhaskar, Kamiya, Narutoshi, Hayami, Tomonori, Fukuda, Ikuo, Fukunishi, Yoshifumi, Nakamura, Haruki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052515/
https://ncbi.nlm.nih.gov/pubmed/31608410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzz029
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