A Penicillin Derivative Exerts an Anti-Metastatic Activity in Melanoma Cells Through the Downregulation of Integrin αvβ3 and Wnt/β-Catenin Pathway

The synthetic triazolylpeptidyl penicillin derivative, named TAP7f, has been previously characterized as an effective antitumor agent in vitro and in vivo against B16-F0 melanoma cells. In this study, we investigated the anti-metastatic potential of this compound on highly metastatic murine B16-F10...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Barrionuevo, Elizabeth, Cayrol, Florencia, Cremaschi, Graciela A., Cornier, Patricia G., Boggián, Dora B., Delpiccolo, Carina M. L., Mata, Ernesto G., Roguin, Leonor P., Blank, Viviana C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052307/
https://ncbi.nlm.nih.gov/pubmed/32158394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00127
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