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ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome

OBJECTIVES: Anti-citrullinated protein antibodies (ACPAs) are a group of autoantibodies targeted against citrullinated proteins/peptides and are informative rheumatoid arthritis (RA) biomarkers. ACPAs also play a crucial role in RA pathogenesis, and their underlying mechanism merits investigation. M...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Dong, Xiwen, Zheng, Zhaohui, Lin, Peng, Fu, Xianghui, Li, Fanni, Jiang, Jianli, Zhu, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052171/
https://ncbi.nlm.nih.gov/pubmed/30911117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0201-9
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