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Low dose radiation (LDR) primed iNOS+ (M1) macrophages modulate angiogenic programming of tumor derived endothelium

Solid tumors are covered by stroma, which is hypoxic in nature and composed of various non-malignant componants such as endothelial cells, fibroblasts and pericytes that support tumor growth. Tumor stroma represents a mechanical barrier for tumor infiltration of CD8+ effector T cells in particular....

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Publicat a:Mol Carcinog
Autors principals: Nadella, Vinod, Singh, Sandhya, Jain, Aklank, Jain, Manju, Vasquez, Karen M, Sharma, Ashok, Tanwar, Pranay, Rath, GK, Prakash, Hridayesh
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051861/
https://ncbi.nlm.nih.gov/pubmed/30035346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22879
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