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Homocysteine Disrupts Outgrowth of Microvascular Endothelium by an iNOS-dependent Mechanism

OBJECTIVE: To test the hypothesis that homocysteine (Hcy) impairs angiogenic outgrowth through an inducible nitric oxide synthase (iNOS)-dependent mechanism. METHODS: Adult C57Bl/6 mouse choroid explants were used in angiogenic outgrowth assays. Mouse microvascular endothelial cells were studied in...

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Autors principals: Mayo, Jamie N., Chen, Cheng-Hung, Liao, Francesca-Fang, Bearden, Shawn E.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126873/
https://ncbi.nlm.nih.gov/pubmed/24655004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12133
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