Evaluation of Intense Androgen Deprivation Before Prostatectomy: A Randomized Phase II Trial of Enzalutamide and Leuprolide With or Without Abiraterone

PURPOSE: Patients with locally advanced prostate cancer have an increased risk of cancer recurrence and mortality. In this phase II trial, we evaluate neoadjuvant enzalutamide and leuprolide (EL) with or without abiraterone and prednisone (ELAP) before radical prostatectomy (RP) in men with locally...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: McKay, Rana R., Ye, Huihui, Xie, Wanling, Lis, Rosina, Calagua, Carla, Zhang, Zhenwei, Trinh, Quoc-Dien, Chang, Steven L., Harshman, Lauren C., Ross, Ashley E., Pienta, Kenneth J., Lin, Daniel W., Ellis, William J., Montgomery, Bruce, Chang, Peter, Wagner, Andrew A., Bubley, Glenn J., Kibel, Adam S., Taplin, Mary-Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2019
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ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051849/
https://ncbi.nlm.nih.gov/pubmed/30811282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.01777
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