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Evaluation of Intense Androgen Deprivation Before Prostatectomy: A Randomized Phase II Trial of Enzalutamide and Leuprolide With or Without Abiraterone

PURPOSE: Patients with locally advanced prostate cancer have an increased risk of cancer recurrence and mortality. In this phase II trial, we evaluate neoadjuvant enzalutamide and leuprolide (EL) with or without abiraterone and prednisone (ELAP) before radical prostatectomy (RP) in men with locally...

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Pubblicato in:J Clin Oncol
Autori principali: McKay, Rana R., Ye, Huihui, Xie, Wanling, Lis, Rosina, Calagua, Carla, Zhang, Zhenwei, Trinh, Quoc-Dien, Chang, Steven L., Harshman, Lauren C., Ross, Ashley E., Pienta, Kenneth J., Lin, Daniel W., Ellis, William J., Montgomery, Bruce, Chang, Peter, Wagner, Andrew A., Bubley, Glenn J., Kibel, Adam S., Taplin, Mary-Ellen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051849/
https://ncbi.nlm.nih.gov/pubmed/30811282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.01777
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