Evaluation of Intense Androgen Deprivation Before Prostatectomy: A Randomized Phase II Trial of Enzalutamide and Leuprolide With or Without Abiraterone

PURPOSE: Patients with locally advanced prostate cancer have an increased risk of cancer recurrence and mortality. In this phase II trial, we evaluate neoadjuvant enzalutamide and leuprolide (EL) with or without abiraterone and prednisone (ELAP) before radical prostatectomy (RP) in men with locally...

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Veröffentlicht in:J Clin Oncol
Hauptverfasser: McKay, Rana R., Ye, Huihui, Xie, Wanling, Lis, Rosina, Calagua, Carla, Zhang, Zhenwei, Trinh, Quoc-Dien, Chang, Steven L., Harshman, Lauren C., Ross, Ashley E., Pienta, Kenneth J., Lin, Daniel W., Ellis, William J., Montgomery, Bruce, Chang, Peter, Wagner, Andrew A., Bubley, Glenn J., Kibel, Adam S., Taplin, Mary-Ellen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051849/
https://ncbi.nlm.nih.gov/pubmed/30811282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.01777
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