Abiraterone Alone or in Combination With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer With Rising Prostate-Specific Antigen During Enzalutamide Treatment

PURPOSE: Enzalutamide resistance could result from raised androgens and be overcome by combination with abiraterone acetate. PLATO (ClinicalTrials.gov identifier: NCT01995513) interrogated this hypothesis using a randomized, double-blind, placebo-controlled design. PATIENTS AND METHODS: In period on...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Attard, Gerhardt, Borre, Michael, Gurney, Howard, Loriot, Yohann, Andresen-Daniil, Corina, Kalleda, Ranjith, Pham, Trinh, Taplin, Mary-Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2018
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ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118405/
https://ncbi.nlm.nih.gov/pubmed/30028657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2018.77.9827
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