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Site-resolved and quantitative characterization of very weak protein-ligand interactions
Very weak interactions between small organic molecules and proteins have long been predicted and are expected to have dissociation constants of 100s of mM and above. Unfortunately, quantitative evaluation of binding in a high-resolution structural context for this affinity regime is particularly dif...
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| Vydáno v: | ACS Chem Biol |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7051831/ https://ncbi.nlm.nih.gov/pubmed/31246002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00353 |
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