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Site-resolved and quantitative characterization of very weak protein-ligand interactions
Very weak interactions between small organic molecules and proteins have long been predicted and are expected to have dissociation constants of 100s of mM and above. Unfortunately, quantitative evaluation of binding in a high-resolution structural context for this affinity regime is particularly dif...
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| 出版年: | ACS Chem Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7051831/ https://ncbi.nlm.nih.gov/pubmed/31246002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00353 |
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