A Peptide-Functionalized Magnetic Nanoplatform-Loaded Melatonin for Targeted Amelioration of Fibrosis in Pressure Overload-Induced Cardiac Hypertrophy

INTRODUCTION: Currently, the unsatisfactory treatment of cardiac hypertrophy is due to the unbridled myocardial fibrosis. Melatonin has been demonstrated to ameliorate cardiac hypertrophy and its accompanied fibrosis in previous studies. But it is not clinically appealing due to its short-lasting ti...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zhao, Xueli, Wang, Xuanying, Wang, Jing, Yuan, Jiani, Zhang, Juan, Zhu, Xiaoli, Lei, Changhui, Yang, Qianli, Wang, Bo, Cao, Feng, Liu, Liwen
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051809/
https://ncbi.nlm.nih.gov/pubmed/32161461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S235518
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