A Peptide-Functionalized Magnetic Nanoplatform-Loaded Melatonin for Targeted Amelioration of Fibrosis in Pressure Overload-Induced Cardiac Hypertrophy

INTRODUCTION: Currently, the unsatisfactory treatment of cardiac hypertrophy is due to the unbridled myocardial fibrosis. Melatonin has been demonstrated to ameliorate cardiac hypertrophy and its accompanied fibrosis in previous studies. But it is not clinically appealing due to its short-lasting ti...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Zhao, Xueli, Wang, Xuanying, Wang, Jing, Yuan, Jiani, Zhang, Juan, Zhu, Xiaoli, Lei, Changhui, Yang, Qianli, Wang, Bo, Cao, Feng, Liu, Liwen
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051809/
https://ncbi.nlm.nih.gov/pubmed/32161461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S235518
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