Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS

OBJECTIVE: To explore the repertoire of glycan-specific immunoglobulin G (IgG) antibodies in treatment-naive patients with relapsing-remitting multiple sclerosis (RRMS). METHODS: A systems-level approach combined with glycan array technologies was used to determine specificities and binding reactivi...

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Publicat a:Neurol Neuroimmunol Neuroinflamm
Autors principals: Boligan, Kayluz F., Oechtering, Johanna, Keller, Christian W., Peschke, Benjamin, Rieben, Robert, Bovin, Nicolai, Kappos, Ludwig, Cummings, Richard D., Kuhle, Jens, von Gunten, Stephan, Lünemann, Jan D.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051216/
https://ncbi.nlm.nih.gov/pubmed/32014849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000676
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