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Repurposing ribosome-targeting antibiotics to overcome resistance to venetoclax in acute myeloid leukemia

Venetoclax, a selective B-cell lymphoma 2 inhibitor, has shown promise in the treatment of acute myeloid leukemia. However, the development of drug resistance limits its clinical efficacy. In our study, we discovered that ribosome-targeting antibiotics can be repurposed to overcome venetoclax resist...

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Détails bibliographiques
Publié dans:Mol Cell Oncol
Auteurs principaux: Sharon, David, Chan, Steven M.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051130/
https://ncbi.nlm.nih.gov/pubmed/32158926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1712182
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