A Novel Antiparasitic Compound Kills Ring-Stage Plasmodium falciparum and Retains Activity Against Artemisinin-Resistant Parasites

Spreading antimalarial resistance threatens effective treatment of malaria, an infectious disease caused by Plasmodium parasites. We identified a compound, BCH070, that inhibits asexual growth of multiple antimalarial-resistant strains of Plasmodium falciparum (half maximal inhibitory concentration...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Clements, Rebecca L, Streva, Vincent, Dumoulin, Peter, Huang, Weigang, Owens, Edward, Raj, Dipak K, Burleigh, Barbara, Llinás, Manuel, Winzeler, Elizabeth A, Zhang, Qisheng, Dvorin, Jeffrey D
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050989/
https://ncbi.nlm.nih.gov/pubmed/31616928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz534
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