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Structural Mechanisms of PTEN Regulation
The tumor suppressor phosphatase and tensin homolog on chromosome 10 (PTEN) is a tightly regulated enzyme responsible for dephosphorylating the progrowth lipid messenger molecule phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) on the plasma membrane. The carboxy-terminal tail (CTT) of PTEN is key...
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| Publicado no: | Cold Spring Harb Perspect Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7050585/ https://ncbi.nlm.nih.gov/pubmed/31636093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036152 |
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