CURRENT OUTCOMES WHEN OPTIMIZING “STANDARD” SAMPLE PREPARATION FOR SINGLE-PARTICLE CRYO-EM

Although high-resolution single-particle electron cryo-microscopy (cryo-EM) is now producing a rapid stream of breakthroughs in structural biology, it nevertheless remains the case that the preparation of suitable frozen-hydrated samples on electron microscopy grids is often quite challenging. Purif...

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Bibliographic Details
Published in:J Microsc
Main Authors: Carragher, Bridget, Cheng, Yifan, Frost, Adam, Glaeser, Robert M., Lander, Gabriel C., Nogales, Eva, Wang, Hong-Wei
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050573/
https://ncbi.nlm.nih.gov/pubmed/31553060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jmi.12834
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