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PARP and PARG inhibitors in cancer treatment
Oxidative and replication stress underlie genomic instability of cancer cells. Amplifying genomic instability through radiotherapy and chemotherapy has been a powerful but nonselective means of killing cancer cells. Precision medicine has revolutionized cancer therapy by putting forth the concept of...
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| Pubblicato in: | Genes Dev |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7050487/ https://ncbi.nlm.nih.gov/pubmed/32029455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.334516.119 |
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