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PARP and PARG inhibitors in cancer treatment

Oxidative and replication stress underlie genomic instability of cancer cells. Amplifying genomic instability through radiotherapy and chemotherapy has been a powerful but nonselective means of killing cancer cells. Precision medicine has revolutionized cancer therapy by putting forth the concept of...

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Bibliografski detalji
Izdano u:Genes Dev
Glavni autor: Slade, Dea
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050487/
https://ncbi.nlm.nih.gov/pubmed/32029455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.334516.119
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