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Genetically Encoding Photocaged Quinone Methide to Multi-Target Protein Residues Covalently in vivo

Genetically introducing covalent bonds into proteins in vivo with residue specificity is affording innovative ways for protein research and engineering, yet latent bioreactive unnatural amino acids (Uaas) genetically encoded to date react with one to few natural residues only, limiting the variety o...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Liu, Jun, Li, Shanshan, Aslam, Nayyar A., Zheng, Feng, Yang, Bing, Cheng, Rujin, Wang, Nanxi, Rozovsky, Sharon, Wang, Peng G., Wang, Qian, Wang, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050464/
https://ncbi.nlm.nih.gov/pubmed/31184146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b01738
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