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Neuron-specific Kv1.1 deficiency is sufficient to cause epilepsy, premature death, and cardiorespiratory dysregulation

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy-related mortality, but the precise cellular substrates involved remain elusive. Epilepsy-associated ion channel genes with co-expression in brain and heart have been proposed as SUDEP candidate genes since they provide a si...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Trosclair, Krystle, Dhaibar, Hemangini A, Gautier, Nicole M, Mishra, Vikas, Glasscock, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050436/
https://ncbi.nlm.nih.gov/pubmed/31978607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104759
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