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Genetic ablation or pharmacological inhibition of Kv1.1 potassium channel subunits impairs atrial repolarization in mice

Voltage-gated Kv1.1 potassium channel α-subunits, encoded by the Kcna1 gene, have traditionally been regarded as neural-specific with no expression or function in the heart. However, recent data revealed that Kv1.1 subunits are expressed in atria where they may have an overlooked role in controlling...

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Publicat a:Am J Physiol Cell Physiol
Autors principals: Si, Man, Trosclair, Krystle, Hamilton, Kathryn A., Glasscock, Edward
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397341/
https://ncbi.nlm.nih.gov/pubmed/30427720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00335.2018
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