Mice Lacking Adenosine 2A Receptor Reveal Increased Severity of MCD-induced NASH

Adenosine 2A receptor (A(2A)R) exerts a protective role in obesity-related non-alcoholic fatty liver disease. Here, we examined whether A(2A)R protects against non-alcoholic steatohepatitis (NASH). In C57BL/6J mice, feeding a methionine- and choline-deficient diet (MCD) resulted in significant weigh...

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Vydáno v:J Endocrinol
Hlavní autoři: Zhou, Jing, Li, Honggui, Cai, Yuli, Ma, Linqiang, Matthews, Destiny, Lu, Bangchao, Zhu, Bilian, Chen, Yanming, Qian, Xiaoxian, Xiao, Xiaoqiu, Li, Qifu, Guo, Shaodong, Huo, Yuqing, Zhao, Liang, Tian, Yanan, Li, Qingsheng, Wu, Chaodong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050433/
https://ncbi.nlm.nih.gov/pubmed/31505462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-19-0198
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