Disruption of Adenosine 2A Receptor Exacerbates NAFLD through Increasing Inflammatory Responses and SREBP1c Activity

Adenosine 2A receptor (A(2A)R) exerts protective roles in endotoxin- and/or ischemia-induced tissue damages. However, the role for A(2A)R in non-alcoholic fatty liver disease (NAFLD) remains largely unknown. We sought to examine the effects of global and/or myeloid cell-specific A(2A)R disruption on...

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Bibliografiska uppgifter
I publikationen:Hepatology
Huvudupphovsmän: Cai, Yuli, Li, Honggui, Liu, Mengyang, Pei, Ya, Zheng, Juan, Zhou, Jing, Luo, Xianjun, Huang, Wenya, Ma, Linqiang, Yang, Qiuhua, Guo, Shaodong, Xiao, Xiaoqiu, Li, Qifu, Zeng, Tianshu, Meng, Fanyin, Francis, Heather, Glaser, Shannon, Chen, Lulu, Huo, Yuqing, Alpini, Gianfranco, Wu, Chaodong
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033664/
https://ncbi.nlm.nih.gov/pubmed/29315766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29777
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