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ApoE and cerebral insulin: trafficking, receptors, and resistance

Central nervous system (CNS) insulin resistance is associated with Alzheimer’s disease (AD). In addition, the apolipoprotein E4 (apoE4) isoform is a risk factor for AD. The connection between these two factors in relation to AD is being actively explored. We summarize this literature with a focus on...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Rhea, Elizabeth M., Raber, Jacob, Banks, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050417/
https://ncbi.nlm.nih.gov/pubmed/31978603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104755
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