Examining the Effect of Hypertonic Saline Administered for Reduction of Intracranial Hypertension on Coagulation

BACKGROUND: Hypertonic saline (23.4%, HTS) bolus administration is common practice for refractory intracranial hypertension, but its effects on coagulation are unknown. We hypothesize that 23.4% HTS in whole blood results in progressive impairment of coagulation in vitro and in vivo in a murine mode...

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Detalhes bibliográficos
Publicado no:J Am Coll Surg
Main Authors: Coleman, Julia R, Moore, Ernest E, Silliman, Christopher C, Stettler, Gregory R, Nunns, Geoffrey R, Samuels, Jason M, Bartley, Matthew G, Vigneshwar, Navin G, Cohen, Mitchell J, Fragoso, Miguel, Sauaia, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050279/
https://ncbi.nlm.nih.gov/pubmed/31843691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2019.11.011
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