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Irbesartan Attenuates Gentamicin-induced Nephrotoxicity in Rats through Modulation of Oxidative Stress and Endogenous Antioxidant Capacity

BACKGROUND: Overproduction of reactive oxygen species and free radicals is the main mechanism beyond gentamicin-induced nephrotoxicity. Irbesartan and other angiotensin II blockers offer significant nephroprotective effect through improvement of renal function and reduction of renal inflammation. Th...

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Bibliografski detalji
Izdano u:Int J Prev Med
Glavni autori: Al-kuraishy, Hayder M., Al-Gareeb, Ali I., Al-nami, Marwa S.
Format: Artigo
Jezik:Inglês
Izdano: Wolters Kluwer - Medknow 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050237/
https://ncbi.nlm.nih.gov/pubmed/32175056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/ijpvm.IJPVM_567_18
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