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Irbesartan Attenuates Gentamicin-induced Nephrotoxicity in Rats through Modulation of Oxidative Stress and Endogenous Antioxidant Capacity
BACKGROUND: Overproduction of reactive oxygen species and free radicals is the main mechanism beyond gentamicin-induced nephrotoxicity. Irbesartan and other angiotensin II blockers offer significant nephroprotective effect through improvement of renal function and reduction of renal inflammation. Th...
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Publicado no: | Int J Prev Med |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Wolters Kluwer - Medknow
2020
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7050237/ https://ncbi.nlm.nih.gov/pubmed/32175056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/ijpvm.IJPVM_567_18 |
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