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Effects of propofol on colon cancer metastasis through STAT3/HOTAIR axis by activating WIF‐1 and suppressing Wnt pathway

BACKGROUND: In the present study, we aim to investigate the potential role of propofol in the tumor progression of colon cancer. METHODS: Human colon cancer cell lines were cultured and exposed with 8 μg/mL propofol. RNA interference was performed to silence the expression of HOTAIR or STAT3 to expl...

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Bibliografske podrobnosti
izdano v:Cancer Med
Main Authors: Zhang, Yun‐Fei, Li, Chang‐Sheng, Zhou, Yi, Lu, Xi‐Hua
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050102/
https://ncbi.nlm.nih.gov/pubmed/31953926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2840
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