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Twin enzymes, divergent control: The cholesterogenic enzymes DHCR14 and LBR are differentially regulated transcriptionally and post-translationally

Cholesterol synthesis is a tightly regulated process, both transcriptionally and post-translationally. Transcriptional control of cholesterol synthesis is relatively well-understood. However, of the ∼20 enzymes in cholesterol biosynthesis, post-translational regulation has only been examined for a s...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Capell-Hattam, Isabelle M., Sharpe, Laura J., Qian, Lydia, Hart-Smith, Gene, Prabhu, Anika V., Brown, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049974/
https://ncbi.nlm.nih.gov/pubmed/31911440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011323
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