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The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally

Cholesterol is essential to human health, and its levels are tightly regulated by a balance of synthesis, uptake, and efflux. Cholesterol synthesis requires the actions of more than twenty enzymes to reach the final product, through two alternate pathways. Here we describe a physical and functional...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Luu, Winnie, Hart-Smith, Gene, Sharpe, Laura J., Brown, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373745/
https://ncbi.nlm.nih.gov/pubmed/25637936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M056986
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