Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase

Gram-positive bacteria, including major clinical pathogens such as Staphylococcus aureus, are becoming increasingly drug-resistant. Their cell walls are composed of a thick layer of peptidoglycan (PG) modified by the attachment of wall teichoic acid (WTA), an anionic glycopolymer that is linked to p...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Li, Franco K. K., Rosell, Federico I., Gale, Robert T., Simorre, Jean-Pierre, Brown, Eric D., Strynadka, Natalie C. J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2020
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049971/
https://ncbi.nlm.nih.gov/pubmed/31969390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011469
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