Molecular characterization of a fungal cyclophilin allergen Rhi o 2 and elucidation of antigenic determinants responsible for IgE–cross-reactivity

Cyclophilins are structurally conserved pan-allergens showing extensive cross-reactivity. So far, no precise information on cross-reactive IgE-epitopes of cyclophilins is available. Here, an 18-kDa IgE-reactive cyclophilin (Rhi o 2) was purified from Rhizopus oryzae, an indoor mold causing allergic...

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Vydáno v:J Biol Chem
Hlavní autoři: Sircar, Gaurab, Bhowmik, Moumita, Sarkar, Rajat Kanti, Najafi, Nazanin, Dasgupta, Angira, Focke-Tejkl, Margarete, Flicker, Sabine, Mittermann, Irene, Valenta, Rudolf, Bhattacharya, Kashinath, Gupta Bhattacharya, Swati
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049968/
https://ncbi.nlm.nih.gov/pubmed/31882546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011659
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