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Flexible IgE epitope containing domains of Phl p 5 cause high allergenic activity
This is the first study determining the three-dimensional structure of Phl p 5a which reveals a novel mechanism for high allergenic activity based on flexibly connected IgE-reactive domains which cross-link effector cell-bound IgE more efficiently than isolated rigid globular proteins. These finding...
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| Pubblicato in: | J Allergy Clin Immunol |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5632575/ https://ncbi.nlm.nih.gov/pubmed/28532654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.05.005 |
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