Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacterium tuberculosis in Macaques

Rationale: Direct evidence for persistence of Mycobacterium tuberculosis (Mtb) during asymptomatic latent tuberculosis infection (LTBI) in humans is currently lacking. Moreover, although a 12-week regimen of once-weekly isoniazid and rifapentine (3HP) is currently recommended by the CDC as treatment...

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Bibliografiske detaljer
Udgivet i:Am J Respir Crit Care Med
Main Authors: Foreman, Taylor W., Bucşan, Allison N., Mehra, Smriti, Peloquin, Charles, Doyle, Lara A., Russell-Lodrigue, Kasi, Gandhi, Neel R., Altman, John, Day, Cheryl L., Ernst, Joel D., Blumberg, Henry M., Rengarajan, Jyothi
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2020
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049922/
https://ncbi.nlm.nih.gov/pubmed/31647877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201903-0646OC
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