UHMK1 promotes gastric cancer progression through reprogramming nucleotide metabolism

UHMK1 is a nuclear serine/threonine kinase recently implicated in carcinogenesis. However, the functions and action mechanisms of UHMK1 in the pathogenesis of human gastric cancer (GC) are unclear. Here, we observed that UHMK1 was markedly upregulated in GC. UHMK1 silencing strongly inhibited GC agg...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Feng, Xing, Ma, Dong, Zhao, Jiabao, Song, Yongxi, Zhu, Yuekun, Zhou, Qingxin, Ma, Fei, Liu, Xing, Zhong, Mengya, Liu, Yu, Xiong, Yubo, Qiu, Xingfeng, Zhang, Zhen, Zhang, Heng, Zhao, Yongxiang, Zhang, Kaiguang, Hong, Xuehui, Zhang, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049804/
https://ncbi.nlm.nih.gov/pubmed/31975428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102541
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