FAM134B oligomerization drives endoplasmic reticulum membrane scission for ER‐phagy

Degradation of endoplasmic reticulum (ER) by selective autophagy (ER‐phagy) is crucial for ER homeostasis. However, it remains unclear how ER scission is regulated for subsequent autophagosomal sequestration and lysosomal degradation. Here, we show that oligomerization of ER‐phagy receptor FAM134B (...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Jiang, Xiao, Wang, Xinyi, Ding, Xianming, Du, Mengjie, Li, Boran, Weng, Xialian, Zhang, Jingzi, Li, Lin, Tian, Rui, Zhu, Qi, Chen, She, Wang, Liang, Liu, Wei, Fang, Lei, Neculai, Dante, Sun, Qiming
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049798/
https://ncbi.nlm.nih.gov/pubmed/31930741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102608
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