Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy

FAM134B/RETREG1 is a selective ER-phagy receptor that regulates the size and shape of the endoplasmic reticulum. The structure of its reticulon-homology domain (RHD), an element shared with other ER-shaping proteins, and the mechanism of membrane shaping remain poorly understood. Using molecular mod...

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Publicat a:Nat Commun
Autors principals: Bhaskara, Ramachandra M., Grumati, Paolo, Garcia-Pardo, Javier, Kalayil, Sissy, Covarrubias-Pinto, Adriana, Chen, Wenbo, Kudryashev, Mikhail, Dikic, Ivan, Hummer, Gerhard
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542808/
https://ncbi.nlm.nih.gov/pubmed/31147549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10345-3
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