Molecular epidemiology and hematologic characterization of δβ-thalassemia and hereditary persistence of fetal hemoglobin in 125,661 families of greater Guangzhou area, the metropolis of southern China

BACKGROUND: Individuals with δβ-thalassemia/HPFH and β-thalassemia usually present with intermedia or thalassemia major. No large-scale survey on HPFH/δβ-thalassemia in southern China has been reported to date. The purpose of this study was to examine the molecular epidemiology and hematologic chara...

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Veröffentlicht in:BMC Med Genet
Hauptverfasser: Jiang, Fan, Zuo, Liandong, Li, Dongzhi, Li, Jian, Tang, Xuewei, Chen, Guilan, Zhou, Jianying, Lu, Hang, Liao, Can
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049201/
https://ncbi.nlm.nih.gov/pubmed/32111191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-020-0981-x
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