Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism

The binding of lipoprotein lipase (LPL) to GPIHBP1 focuses the intravascular hydrolysis of triglyceride-rich lipoproteins on the surface of capillary endothelial cells. This process provides essential lipid nutrients for vital tissues (e.g., heart, skeletal muscle, and adipose tissue). Deficiencies...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kristensen, Kristian K., Leth-Espensen, Katrine Zinck, Mertens, Haydyn D. T., Birrane, Gabriel, Meiyappan, Muthuraman, Olivecrona, Gunilla, Jørgensen, Thomas J. D., Young, Stephen G., Ploug, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049152/
https://ncbi.nlm.nih.gov/pubmed/32034094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920202117
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