Loss of phenotypic inheritance associated with ydcI mutation leads to increased frequency of small, slow persisters in Escherichia coli

Whenever a genetically homogenous population of bacterial cells is exposed to antibiotics, a tiny fraction of cells survives the treatment, the phenomenon known as bacterial persistence [G.L. Hobby et al., Exp. Biol. Med. 50, 281–285 (1942); J. Bigger, The Lancet 244, 497–500 (1944)]. Despite its bi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hingley-Wilson, Suzanne M., Ma, Nan, Hu, Yin, Casey, Rosalyn, Bramming, Anders, Curry, Richard J., Tang, Hongying Lilian, Wu, Huihai, Butler, Rachel E., Jacobs, William R., Rocco, Andrea, McFadden, Johnjoe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049120/
https://ncbi.nlm.nih.gov/pubmed/32029596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914741117
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