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Slow Protein Fluctuations Explain the Emergence of Growth Phenotypes and Persistence in Clonal Bacterial Populations

One of the most challenging problems in microbiology is to understand how a small fraction of microbes that resists killing by antibiotics can emerge in a population of genetically identical cells, the phenomenon known as persistence or drug tolerance. Its characteristic signature is the biphasic ki...

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Detalhes bibliográficos
Main Authors: Rocco, Andrea, Kierzek, Andrzej M., McFadden, Johnjoe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558523/
https://ncbi.nlm.nih.gov/pubmed/23382887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054272
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