Ultrathin Silicon Membranes for In Situ Optical Analysis of Nanoparticle Translocation Across a Human Blood-Brain Barrier Model

Here we present a blood-brain barrier (BBB) model that enables high-resolution imaging of nanoparticle (NP) interactions with endothelial cells and the capture of rare NP translocation events. The enabling technology is an ultrathin silicon nitride (SiN) membrane (0.5 μm pore size, 20% porosity, 400...

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Bibliographic Details
Published in:ACS Nano
Main Authors: Hudecz, Diána, Khire, Tejas, Chung, Hung Li, Adumeau, Laurent, Glavin, Dale, Luke, Emma, Nielsen, Morten S., Dawson, Kenneth A., McGrath, James L., Yan, Yan
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049097/
https://ncbi.nlm.nih.gov/pubmed/31914314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b08870
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