A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood–brain barrier under flow

Here we report on the development of a breakthrough microfluidic human in vitro cerebrovascular barrier (CVB) model featuring stem cell-derived brain-like endothelial cells (BLECs) and nanoporous silicon nitride (NPN) membranes (µSiM-CVB). The nanoscale thinness of NPN membranes combined with their...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Mossu, Adrien, Rosito, Maria, Khire, Tejas, Li Chung, Hung, Nishihara, Hideaki, Gruber, Isabelle, Luke, Emma, Dehouck, Lucie, Sallusto, Federica, Gosselet, Fabien, McGrath, James L, Engelhardt, Britta
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421249/
https://ncbi.nlm.nih.gov/pubmed/30565961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18820584
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