The journey of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) from lab to clinic

Human immunodeficiency virus (HIV) infection is now pandemic. Targeting HIV-1 reverse transcriptase (HIV-1 RT) has been considered one of the most successful targets for the development of anti-HIV treatment. Among the HIV-1 RT inhibitors, non-nucleoside reverse transcriptase inhibitors (NNRTIs) hav...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Namasivayam, Vigneshwaran, Vanangamudi, Murugesan, Kramer, Victor G., Kurup, Sonali, Zhan, Peng, Liu, Xinyong, Kongsted, Jacob, Byrareddy, Siddappa N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049092/
https://ncbi.nlm.nih.gov/pubmed/30516990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b00843
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