Study on the antibacterial activities of emodin derivatives against clinical drug-resistant bacterial strains and their interaction with proteins

BACKGROUND: Novel haloemodin (HEI2) synthesized by modifying emodin, a traditional Chinese medicine component, possesses remarkable antibacterial activity, being much more effective than its parent nucleus, emodin. METHODS: Firstly, we discovered that HEI2 increases bacterial cell membrane permeabil...

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Библиографические подробности
Опубликовано в: :Ann Transl Med
Главные авторы: Ji, Chengjie, Xin, Guang, Duan, Feixia, Huang, Wen, Tan, Taichang
Формат: Artigo
Язык:Inglês
Опубликовано: AME Publishing Company 2020
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049003/
https://ncbi.nlm.nih.gov/pubmed/32175385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.12.100
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