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Study on the antibacterial activities of emodin derivatives against clinical drug-resistant bacterial strains and their interaction with proteins

BACKGROUND: Novel haloemodin (HEI2) synthesized by modifying emodin, a traditional Chinese medicine component, possesses remarkable antibacterial activity, being much more effective than its parent nucleus, emodin. METHODS: Firstly, we discovered that HEI2 increases bacterial cell membrane permeabil...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Ji, Chengjie, Xin, Guang, Duan, Feixia, Huang, Wen, Tan, Taichang
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049003/
https://ncbi.nlm.nih.gov/pubmed/32175385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.12.100
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