Učitavanje...
Insight into DNA substrate specificity of PARP1-catalysed DNA poly(ADP-ribosyl)ation
DNA-dependent poly(ADP-ribose) polymerases (PARPs) PARP1, PARP2 and PARP3 act as DNA break sensors signalling DNA damage. Upon detecting DNA damage, these PARPs use nicotine adenine dinucleotide as a substrate to synthesise a monomer or polymer of ADP-ribose (MAR or PAR, respectively) covalently att...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7048826/ https://ncbi.nlm.nih.gov/pubmed/32111879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60631-0 |
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