Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal and incurable form of interstitial lung disease in which persistent injury results in scar tissue formation. As fibrosis thickens, the lung tissue loses the ability to facilitate gas exchange and provide cells with needed oxygen. Currently, IPF has few...

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Pubblicato in:Nat Commun
Autori principali: Dinh, Phuong-Uyen C., Paudel, Dipti, Brochu, Hayden, Popowski, Kristen D., Gracieux, M. Cyndell, Cores, Jhon, Huang, Ke, Hensley, M. Taylor, Harrell, Erin, Vandergriff, Adam C., George, Arianna K., Barrio, Raina T., Hu, Shiqi, Allen, Tyler A., Blackburn, Kevin, Caranasos, Thomas G., Peng, Xinxia, Schnabel, Lauren V., Adler, Kenneth B., Lobo, Leonard J., Goshe, Michael B., Cheng, Ke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048814/
https://ncbi.nlm.nih.gov/pubmed/32111836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14344-7
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