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Effect direction meta-analysis of GWAS identifies extreme, prevalent and shared pleiotropy in a large mammal
In genome-wide association studies (GWAS), variants showing consistent effect directions across populations are considered as true discoveries. We model this information in an Effect Direction MEta-analysis (EDME) to quantify pleiotropy using GWAS of 34 Cholesky-decorrelated traits in 44,000+ cattle...
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| Опубликовано в: : | Commun Biol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7048789/ https://ncbi.nlm.nih.gov/pubmed/32111961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0823-6 |
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