Histological Characterization of Aldosterone-producing Adrenocortical Adenomas with Different Somatic Mutations

CONTEXT: Aldosterone-producing adrenocortical adenomas (APAs) are mainly composed of clear (lipid rich) and compact (eosinophilic) tumor cells. The detailed association between these histological features and somatic mutations (KCNJ5, ATP1A1, ATP2B3, and CACNA1D) in APAs is unknown. OBJECTIVE: To ex...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Ono, Yoshikiyo, Yamazaki, Yuto, Omata, Kei, Else, Tobias, Tomlins, Scott A, Rhayem, Yara, Williams, Tracy Ann, Reincke, Martin, Carling, Tobias, Monticone, Silvia, Mulatero, Paolo, Beuschlein, Felix, Ito, Sadayoshi, Satoh, Fumitoshi, Rainey, William E, Sasano, Hironobu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Online Only
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048684/
https://ncbi.nlm.nih.gov/pubmed/31789380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz235
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