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Ischemic neuroprotectant PKCε restores mitochondrial glutamate oxaloacetate transaminase in the neuronal NADH shuttle after ischemic injury
The preservation of mitochondrial function is a major protective strategy for cerebral ischemic injuries. Previously our laboratory demonstrated that protein kinase C epsilon (PKCε) promotes the synthesis of mitochondrial Nicotinamide adenine dinucleotide (NAD(+)). NAD(+) along with its reducing equ...
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| Veröffentlicht in: | Transl Stroke Res |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7048657/ https://ncbi.nlm.nih.gov/pubmed/31473978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-019-00729-4 |
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